Make Hand Sanitizer Gel using HPMC to replace of Carbomer

Make Hand Sanitizer Gel using HPMC to replace of Carbomer

Hand sanitizer gel is a crucial product in maintaining hand hygiene and preventing the spread of infectious diseases. Carbomer is a commonly used thickening agent in hand sanitizer gel formulations. However, if you want to replace Carbomer with HPMC (Hydroxypropyl Methylcellulose), you can use the following recipe:


  • Isopropyl alcohol (70% or higher)
  • HPMC
  • Glycerin
  • Hydrogen peroxide (3%)
  • Distilled water


  1. In a clean and sterilized container, add 20g of HPMC to 500 ml of distilled water.
  2. Stir the mixture continuously for 2-3 hours until the HPMC is completely dissolved.
  3. Add 20 ml of glycerin to the mixture and stir until fully incorporated.
  4. Add 15 ml of hydrogen peroxide and stir again.
  5. Slowly add 300 ml of isopropyl alcohol to the mixture, while continuously stirring.
  6. Keep stirring the mixture until it becomes a gel-like consistency.
  7. Transfer the mixture to a sterilized bottle or dispenser.

Note: The amount of isopropyl alcohol can be adjusted based on the desired alcohol concentration of the hand sanitizer gel. It is recommended to use a concentration of at least 70% isopropyl alcohol for optimal effectiveness. Also, please note that HPMC may not provide the same thickening properties as Carbomer, so you may need to adjust the amount used to achieve the desired consistency.

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